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doi: 10.3389/fimmu.2022.941556 181 DiDomenicoJLamanoJBOyonDLiYVeliceasaDKaurGet al

& Gutirrez, R

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SLC7A11 binds directly to ALOX12 and inhibits its lipoxygenase activity[40], which offsets P53-mediated ferroptosis induced by ROS stress and reverses P53-dependent tumor growth suppression in xenograft models[40]