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Clinical research has primarily employed intravenous infusions at high doses, though subcutaneous administration at lower doses is emerging as a practical maintenance route [2] [3]

Note on visceral (smooth-muscle) cramps: Cramping sensations in the abdomen or chest (e.g., oesophageal spasm) or gut are typically due to visceral smooth-muscle activity or underlying organ pathology (e.g., colic, biliary colic, bowel obstruction, oesophageal spasm) and should be evaluated differently from skeletal muscle cramps

3-Year follow-up of temporary implantable nitinol device implantation for the treatment of benign prostatic obstruction

ETD, estimated treatment difference

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