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showed that glycyrrhizin can prevent ferroptosis in cells and in an animal model of acute liver failure by regulating iron levels, the GSH/GPX4 pathway, and the NRF2/HO-1/HMGB1 pathway

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doi: 10.1016/j.freeradbiomed.2011.06.011 136

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Kurniawan et al., 2016

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Release of cathepsin B in cytosol causes cell death in acute pancreatitis

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Oxygen deprivation (hypoxia) represents the immediate result, since intestinal cells are deprived of the oxygen necessary for mitochondrial oxidative phosphorylation, the major process for creating ATP (Weinberg et al., 2000

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Non-canonical (non-SMAD2/3) TGF-beta signaling in fibrosis: Mechanisms and targets

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