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and on the other hand, inhibiting the PERK/eIF2/CHOP apoptotic signaling axis and the subsequent activation of caspase-12 and caspase-3, thereby reducing dopaminergic neuronal apoptosis and improving motor function in PD models (55)

Whole genome metagenomic sequencing is the process of breaking the whole genomic DNA into multiple fragments, directly sequencing these molecular fragments, and then analyzing the data after preprocessing (including sequencing quality control and contaminated sequence elimination) to understand the structure of the entire microbial community (Shi et al., 2022)

PUD results from an imbalance between the protective (e.g., mucus, bicarbonate, prostaglandins, antioxidant system and cell proliferation) and destructive (e.g., gastric acid, pepsin, Helicobacter pylori , stress, nonsteroidal anti-inflammatory drugs (NSAIDs) and alcohol) factors (Laine et al

Data have been reported for lower SOD and CAT levels in patients with bipolar disorder than in a healthy control group (45)

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