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A.SchmalfussE.WinterhalterP.et al (2016)

The PubMed, Cochrane Library, OvidSP, Web of Science, China Science and Technology Journal Database, Chinese National Knowledge Infrastructure and China Wanfang Standards Database databases were systematically searched from the inception dates to October 1st, 2019, using the key wordsglutathione or GSH and Parkinson or Parkinson's disease or PD

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Laboratory investigations comprised creatine phosphokinase, liver enzymes, and a comprehensive metabolic workup, including blood lactate, ammonia, plasma amino acids, acylcarnitine profile, urine organic acids, very-long-chain fatty acids, glucose, and cerebrospinal fluid neurotransmitters, according to standard clinical protocols

One very elegant design is to use a form of B12 that can be detected by rather sophisticated methodologies in a blood sample

They should be applied consistently throughout the day, rather than on an as-needed basis, to prevent symptom exacerbation [6]