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Any dosing protocols discussed online are experimental and intended for research settings rather than clinical use

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Some notice an immediate boost in energy and focus, while others experience more gradual improvements over the following days

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Patients, Material, and Methods Between 2015 and 2016, 66 patients with ME/CFS were studied ( The usual care of the study participants included a detailed clinical history, physical examination, vitamin B12 serum levels (pmol/l), and ECG and echocardiography

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This process is termed as the methyl trap hypothesis

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Whilst many symptoms improve with appropriate B12 treatment, not all resolve completely, especially if neurological damage was severe or prolonged before treatment commenced

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