melanotic macule increased melanocytes macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight ⬆️ in single basal melanocytes; NO nests. More info like this in Melanocyte - an overview |

Melanocyte an overview ScienceDirect Topics Melanocytic nevi and melanoma: unraveling a complex relationship Oncogene Pigmented lesions of the oral cavity: An Update PMC Labial Lentigo (labial melanotic macule) Cancer Therapy Advisor Pigmented skin lesions are areas of increased melanin or melanocytic proliferation that range from common benign findings to lesions requiring closer clinical evaluation. Recognizing the characteristic features of common benign pigmented skin Smoker's Melanosis Benign oral mucosal pigmentation seen in smokers Due to increased melanin production, not melanocyte number Clinical Diffuse brown macules patches Usually flat, irregular Most common

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