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Vitamin B12 Intramuscular Dosage Guidelines The intramuscular route is often preferred for Vitamin B12 injections

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When to seek medical help See a doctor promptly if you have spreading redness or warmth around the site, discharge or a fever, numbness or weakness that does not settle, or any swelling of the face, lips or throat or difficulty breathing, which can signal a rare allergic reaction and is a medical emergency

Because vitamin B12 (cobalamin) is a water-soluble vitamin and your body excretes it daily in your urine, it doesnt build up in the body like fat-soluble vitaminslike vitamin Ddo