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AOD-9604, sometimes called the fat-burning peptide, showed limited promise in animal studies but has failed to demonstrate consistent results in people, leading the FDA to explicitly state it is not an approved treatment (FDA on unapproved drugs)

Its dual mechanism works similarly to tirzepatide (Mounjaro/Wegovy)

Discovery of a class of endogenous mammalian lipids with anti-diabetic and anti-inflammatory effects

Cartilage Health A single rabbit study showed increased cartilage production when HGH Fragment was combined with hyaluronic acid

But the primary driver for most tesamorelin prescriptions is visceral fat reduction: this is where this peptide genuinely outperforms its alternatives

How long this lasts depends on how well the patient responds and the severity of the deficiency