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Tannins significantly reduced the phase I and phase II enzyme activities in mouse liver tissues ( Salvianolic acid B, a rosmarinic acid dimer, is an active component of Salvia miltiorrhiza Bunge [Lamiaceae], and its reduction of drug-induced liver injury is associated with its antioxidant activity ( Chlorogenic acid, a phenolic compound with various biological activities, ameliorates liver injury in an experimentally induced model of oxidative stress ( Caffeic acid is a common phenolic chemical found in a wide variety of plants

[130] reported that curcumin-derived CQDs demonstrated potent antiviral activity against the Japanese encephalitis virus by selectively binding to its surface envelope protein

E., Glover, D

Nature Communications (2018) 2

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Another source of deficiency can be malabsorption issues, where the body is unable to properly absorb B12 from the intestines due to various gastrointestinal disorders