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Punicalagin contains galloyl groups esterified with glucose, which undergo hydrolysis to form ellagic acid and punicalin (Yamada et al., 2018)

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DOI: Siokas V, Fotiadou A, Dardiotis E, Kotoula MG, Tachmitzi SV, Chatzoulis DZ, et al

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However, an impairment in the respiratory burst was observed in granulocytemacrophage colony-stimulating factor (GM-CSF)-matured MDMs and alveolar macrophage-like (AML) cells 2 from both patients with TNF deficiency, TNF- or TNFR1-deficient induced pluripotent stem (iPS)-cell-derived GM-CSF-matured macrophages, and healthy control MDMs and AML cells differentiated with TNF blockers in vitro, and in lung macrophages treated with TNF blockers ex vivo

This will give them a sense of whether youre not consuming enough iron or may have a condition that inhibits absorption of iron into your blood