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Raw264.7 cells are stimulated by LPS (1 mg/mL) and incubated with Fer-1 (0.1 M), SSe@ZIF-8 (40 g/mL), and FSZ (40 g/mL) for 24 h

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Biochemical assays and ELISA were used to evaluate ovarian oxidative stress markers (GSH and MDA), reproductive hormones (progesterone, estradiol, FSH, and LH), proinflammatory interleukins (IL-8-like cytokine, IL-12, IL-15, and IL-18), and the activities of key steroidogenic enzymes (3-HSD1, 11-HSD1, and 17-HSD1)

Looking at all studies is valuable for providing an overview of all research, important to avoid cherry-picking, and informative when a positive result is found despite combining less-optimal situations

Additionally, three of the six variants exhibited greater sensitivity than the parental p53-null OVCAR5 cells, including the positive control R175H (Fig

We demonstrated that ligands with distinct chemical structures uniquely bind to the receptor, resulting in diverse conformations and biasing signal transduction