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462 Increasing evidence suggests that the development of many forms of cardiovascular diseases, such as heart failure, myocardial infarction, and cardiomyopathy, is driven by ferroptosis (Fig

Results: The particle size, PDI, and zeta potential of BUD-LNPs were 127.63 1.33 nm, 0.27 0.02, and 3.33 0.13 mV, respectively

In eukaryotes and aerobic prokaryotes, GSTs are grouped into at least four major protein families: cytosolic GSTs, mitochondrial GSTs, microsomal GSTs, and bacterial Fosfomycin-resistance proteins [40, 42, 58-59]

In addition, compounds such as curcumin, quercetin, and safflower yellow have been found to activate SIRT1 expression, thereby reducing articular cartilage degradation and inhibiting chondrocyte inflammation and apoptosis [66,67,68]

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doi: 10.1038/npp.2012.78 148 HoyeM