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Clinical evidence comes in tiers: mechanistic studies (does the molecule do what it should at the cellular level?), animal studies (does it produce the expected effect in a living organism?), and human trials (does it actually work on the people who will use it?)

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Role of arsenic (+3 oxidation state) methyltransferase in arsenic mediated APL treatment:An in vitro investigation

However, anaemia and iron and other micronutrient deficiencies may not be as well characterised in the same populations due to challenges around blood testing, potentially leading to the co-occurrence of undernutrition with anaemia being overlooked