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Blood-brain barrier-associated efflux transporters: A significant but underappreciated obstacle to drug development in glioblastoma

Juwik, C

Nutrients 11(11):2579

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Mainwaring GW, Nash J, Davidson M, Green T

However, the presence of ulcers, bleeding, and an imbalance in the mucosal environment can further compromise the integrity of the intestinal mucosal barrier, ultimately resulting in a detrimental cycle of ongoing mucosal damage and destruction, impaired reconstruction capacity, and exacerbated homeostatic imbalance (Chang et al., 2013)